Human-gpDB    A database of human GPCRs, G-proteins, Effectors and their interactions

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	Effectors:                   Cadherins                               Cadherins                                           E cadherin Name Description Gene Names UniProt Acc URLs E cadherin-Homo sapiens RecName: Full=Cadherin-1;AltName: Full=Epithelial cadherin; Short=E-cadherin;AltName: Full=Uvomorulin;AltName: Full=CAM 120/80;AltName: CD_antigen=CD324;Contains: RecName: Full=E-Cad/CTF1;Contains: RecName: Full=E-Cad/CTF2;Contains: RecName: Full=E-Cad/CTF3;Flags: Precursor CDH1; CDHE; UVO P12830 E S V                   Calmodulins                               Calmodulins                                           Calmodulin Name Description Gene Names UniProt Acc URLs Calmodulin-Homo sapiens RecName: Full=Calmodulin; Short=CaM CALM1; CALM; CAM; CAM1 P62158 E S V                   Cyclases                               Adenylate cyclases                                           Adenylate cyclase 1 Name Description Gene Names UniProt Acc URLs Adenylate cyclase 1-Homo sapiens RecName: Full=Adenylate cyclase type 1; EC=4.6.1.1;AltName: Full=Adenylate cyclase type I;AltName: Full=ATP pyrophosphate-lyase 1;AltName: Full=Adenylyl cyclase 1;AltName: Full=Ca(2+)/calmodulin-activated adenylyl cyclase ADCY1 Q08828 E S V                                           Adenylate cyclase 2 Name Description Gene Names UniProt Acc URLs Adenylate cyclase 2-Homo sapiens RecName: Full=Adenylate cyclase type 2; EC=4.6.1.1;AltName: Full=Adenylate cyclase type II;AltName: Full=ATP pyrophosphate-lyase 2;AltName: Full=Adenylyl cyclase 2 ADCY2; KIAA1060 Q08462 E S V                                           Adenylate cyclase 3 Name Description Gene Names UniProt Acc URLs Adenylate cyclase 3-Homo sapiens "RecName: Full=Adenylate cyclase type 3; EC=4.6.1.1;AltName: Full=Adenylate cyclase type III; Short=AC-III;AltName: Full=ATP pyrophosphate-lyase 3;AltName: Full=Adenylyl cyclase 3; Short=AC3;AltName: Full=Adenylate cyclase, olfactive type;" ADCY3; KIAA0511 O60266 E S V                                           Adenylate cyclase 4 Name Description Gene Names UniProt Acc URLs Adenylate cyclase 4-Homo sapiens RecName: Full=Adenylate cyclase type 4; EC=4.6.1.1;AltName: Full=Adenylate cyclase type IV;AltName: Full=ATP pyrophosphate-lyase 4;AltName: Full=Adenylyl cyclase 4 ADCY4 Q8NFM4 E S V                                           Adenylate cyclase 5 Name Description Gene Names UniProt Acc URLs Adenylate cyclase 5-Homo sapiens RecName: Full=Adenylate cyclase type 5; EC=4.6.1.1;AltName: Full=Adenylate cyclase type V;AltName: Full=ATP pyrophosphate-lyase 5;AltName: Full=Adenylyl cyclase 5 ADCY5 O95622 E S V                                           Adenylate cyclase 6 Name Description Gene Names UniProt Acc URLs Adenylate cyclase 6-Homo sapiens RecName: Full=Adenylate cyclase type 6; EC=4.6.1.1;AltName: Full=Adenylate cyclase type VI;AltName: Full=ATP pyrophosphate-lyase 6;AltName: Full=Adenylyl cyclase 6;AltName: Full=Ca(2+)-inhibitable adenylyl cyclase ADCY6; KIAA0422 O43306 E S V                                           Adenylate cyclase 7 Name Description Gene Names UniProt Acc URLs Adenylate cyclase 7-Homo sapiens RecName: Full=Adenylate cyclase type 7; EC=4.6.1.1;AltName: Full=Adenylate cyclase type VII;AltName: Full=ATP pyrophosphate-lyase 7;AltName: Full=Adenylyl cyclase 7 ADCY7; KIAA0037 P51828 E S V                                           Adenylate cyclase 8 Name Description Gene Names UniProt Acc URLs Adenylate cyclase 8-Homo sapiens RecName: Full=Adenylate cyclase type 8; EC=4.6.1.1;AltName: Full=Adenylate cyclase type VIII;AltName: Full=ATP pyrophosphate-lyase 8;AltName: Full=Adenylyl cyclase 8;AltName: Full=Ca(2+)/calmodulin-activated adenylyl cyclase ADCY8 P40145 E S V                                           Adenylate cyclase 9 Name Description Gene Names UniProt Acc URLs Adenylate cyclase 9-Homo sapiens RecName: Full=Adenylate cyclase type 9; EC=4.6.1.1;AltName: Full=Adenylate cyclase type IX;AltName: Full=ATP pyrophosphate-lyase 9;AltName: Full=Adenylyl cyclase 9 ADCY9; KIAA0520 O60503 E S V                   Dynamins                               Dynamins                                           Dynamin 1 Name Description Gene Names UniProt Acc URLs Dynamin 1-Homo sapiens RecName: Full=Dynamin-1; EC=3.6.5.5 DNM1; DNM Q05193 E S V                   Ezrin-radixin-moesin-binding phosphoproteins                               Ezrin-radixin-moesin-binding phosphoproteins                                           EBP50/NHERF 1 Name Description Gene Names UniProt Acc URLs EBP50/NHERF 1-Homo sapiens RecName: Full=Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Short=NHERF-1;AltName: Full=Ezrin-radixin-moesin-binding phosphoprotein 50; Short=EBP50;AltName: Full=Regulatory cofactor of Na(+)/H(+) exchanger;AltName: Full=Sodium-hydrogen exchanger regulatory factor 1;AltName: Full=Solute carrier family 9 isoform A3 regulatory factor 1 SLC9A3R1; NHERF; NHERF1 O14745 E S V                   G-protein-regulated inducers of neurite outgrowth                               G-protein-regulated inducers of neurite outgrowth                                           G-protein-regulated inducer of neurite outgrowth GRIN1 Name Description Gene Names UniProt Acc URLs G-protein-regulated inducer of neurite outgrowth GRIN1-Homo sapiens RecName: Full=G protein-regulated inducer of neurite outgrowth 1; Short=GRIN1 GPRIN1; KIAA1893 Q7Z2K8 E S V                                           G-protein-regulated inducer of neurite outgrowth GRIN2 Name Description Gene Names UniProt Acc URLs G-protein-regulated inducer of neurite outgrowth GRIN2-Homo sapiens RecName: Full=G protein-regulated inducer of neurite outgrowth 2; Short=GRIN2 GPRIN2; KIAA0514 O60269 E S V                   GTPase activating proteins                               Rap-specific GAPs                                           Rap1GAPII Name Description Gene Names UniProt Acc URLs Rap1GAPII-Homo sapiens-1 RecName: Full=Rap1 GTPase-activating protein 1; Short=Rap1GAP1; Short=Rap1GAP RAP1GAP; KIAA0474; RAP1GA1 P47736 E S V Rap1GAPII-Homo sapiens-2 RecName: Full=Rap1 GTPase-activating protein 2; Short=Rap1GAP2;AltName: Full=GTPase-activating Rap/Ran-GAP domain-like protein 4 GARNL4; KIAA1039; RAP1GA2 Q684P5 E S V                               Ras GAPs                                           Ras GAP 2 Name Description Gene Names UniProt Acc URLs Ras GAP 2-Homo sapiens RecName: Full=Ras GTPase-activating protein 2;AltName: Full=GAP1m RASA2; GAP1M; RASGAP Q15283 E S V                   Guanine nucleotide exchange factors                               RhoGEFs                                           LARG RhoGEF Name Description Gene Names UniProt Acc URLs LARG RhoGEF-Homo sapiens RecName: Full=Rho guanine nucleotide exchange factor 12;AltName: Full=Leukemia-associated RhoGEF ARHGEF12; KIAA0382; LARG Q9NZN5 E S V                                           Lbc RhoGEF Name Description Gene Names UniProt Acc URLs Lbc RhoGEF-Homo sapiens RecName: Full=A-kinase anchor protein 13; Short=AKAP-13;AltName: Full=Protein kinase A-anchoring protein 13;AltName: Full=Breast cancer nuclear receptor-binding auxiliary protein;AltName: Full=Human thyroid-anchoring protein 31;AltName: Full=Guanine nucleotide exchange factor Lbc;AltName: Full=AKAP-Lbc;AltName: Full=P47;AltName: Full=Lymphoid blast crisis oncogene; Short=LBC oncogene;AltName: Full=Non-oncogenic Rho GTPase-specific GTP exchange factor AKAP13; BRX; HT31; LBC Q12802 E S V                                           p115 RhoGEF Name Description Gene Names UniProt Acc URLs p115 RhoGEF-Homo sapiens RecName: Full=Rho guanine nucleotide exchange factor 1;AltName: Full=115 kDa guanine nucleotide exchange factor;AltName: Full=p115-RhoGEF;AltName: Full=p115RhoGEF;AltName: Full=Sub1.5 ARHGEF1 Q92888 E S V                                           PDZ RhoGEF Name Description Gene Names UniProt Acc URLs PDZ RhoGEF-Homo sapiens RecName: Full=Rho guanine nucleotide exchange factor 11;AltName: Full=PDZ-RhoGEF ARHGEF11; KIAA0380 O15085 E S V                               Synembryns                                           Synembryn(Ric8a) Name Description Gene Names UniProt Acc URLs Synembryn(Ric8a)-Homo sapiens RecName: Full=Synembryn-A;AltName: Full=Protein Ric-8A RIC8A Q9NPQ8 E S V                   Guanine nucleotide releasing factors                               Ras specific nucleotide releasing factors                                           Ras specific nucleotide exchange factor CDC25 Name Description Gene Names UniProt Acc URLs Ras specific nucleotide exchange factor CDC25-Homo sapiens RecName: Full=Ras-specific guanine nucleotide-releasing factor 1; Short=Ras-GRF1; Short=Guanine nucleotide-releasing factor 1; Short=Guanine nucleotide-releasing protein;AltName: Full=Ras-specific nucleotide exchange factor CDC25 RASGRF1; CDC25; GNRP; GRF1 Q13972 E S V                   Ion channels                               ATP-sensitive inward rectifier potassium channels                                           ATP-sensitive inward rectifier potassium channel 1 Name Description Gene Names UniProt Acc URLs ATP-sensitive inward rectifier potassium channel 1-Homo sapiens "RecName: Full=ATP-sensitive inward rectifier potassium channel 1;AltName: Full=Potassium channel, inwardly rectifying subfamily J member 1;AltName: Full=ATP-regulated potassium channel ROM-K;AltName: Full=Kir1.1;" KCNJ1; ROMK1 P48048 E S V                                           ATP-sensitive inward rectifier potassium channel 10 Name Description Gene Names UniProt Acc URLs ATP-sensitive inward rectifier potassium channel 10-Homo sapiens "RecName: Full=ATP-sensitive inward rectifier potassium channel 10;AltName: Full=Potassium channel, inwardly rectifying subfamily J member 10;AltName: Full=Inward rectifier K(+) channel Kir1.2;AltName: Full=ATP-dependent inwardly rectifying potassium channel Kir4.1;" KCNJ10 P78508 E S V                                           ATP-sensitive inward rectifier potassium channel 11 Name Description Gene Names UniProt Acc URLs ATP-sensitive inward rectifier potassium channel 11-Homo sapiens "RecName: Full=ATP-sensitive inward rectifier potassium channel 11;AltName: Full=Potassium channel, inwardly rectifying subfamily J member 11;AltName: Full=Inward rectifier K(+) channel Kir6.2;AltName: Full=IKATP;" KCNJ11 Q14654 E S V                                           ATP-sensitive inward rectifier potassium channel 12 Name Description Gene Names UniProt Acc URLs ATP-sensitive inward rectifier potassium channel 12-Homo sapiens "RecName: Full=ATP-sensitive inward rectifier potassium channel 12;AltName: Full=Potassium channel, inwardly rectifying subfamily J member 12;AltName: Full=Inward rectifier K(+) channel Kir2.2;AltName: Full=Kir2.2v;AltName: Full=IRK2;" KCNJ12; IRK2; KCNJN1 Q14500 E S V                                           ATP-sensitive inward rectifier potassium channel 14 Name Description Gene Names UniProt Acc URLs ATP-sensitive inward rectifier potassium channel 14-Homo sapiens "RecName: Full=ATP-sensitive inward rectifier potassium channel 14;AltName: Full=Potassium channel, inwardly rectifying subfamily J member 14;AltName: Full=Inward rectifier K(+) channel Kir2.4; Short=IRK4;" KCNJ14 Q9UNX9 E S V                                           ATP-sensitive inward rectifier potassium channel 15 Name Description Gene Names UniProt Acc URLs ATP-sensitive inward rectifier potassium channel 15-Homo sapiens "RecName: Full=ATP-sensitive inward rectifier potassium channel 15;AltName: Full=Potassium channel, inwardly rectifying subfamily J member 15;AltName: Full=Inward rectifier K(+) channel Kir4.2;AltName: Full=Kir1.3;" KCNJ15; KCNJ14 Q99712 E S V                                           ATP-sensitive inward rectifier potassium channel 8 Name Description Gene Names UniProt Acc URLs ATP-sensitive inward rectifier potassium channel 8-Homo sapiens "RecName: Full=ATP-sensitive inward rectifier potassium channel 8;AltName: Full=Potassium channel, inwardly rectifying subfamily J member 8;AltName: Full=Inwardly rectifier K(+) channel Kir6.1;AltName: Full=uKATP-1;" KCNJ8 Q15842 E S V                               Voltage dependent calcium channels                                           Voltage dependent N type calcium channel Name Description Gene Names UniProt Acc URLs Voltage dependent N type calcium channel-Homo sapiens "RecName: Full=Voltage-dependent N-type calcium channel subunit alpha-1B;AltName: Full=Voltage-gated calcium channel subunit alpha Cav2.2;AltName: Full=Calcium channel, L type, alpha-1 polypeptide isoform 5;AltName: Full=Brain calcium channel III; Short=BIII;" CACNA1B; CACH5; CACNL1A5 Q00975 E S V                                           Voltage dependent P/Q type calcium channel Name Description Gene Names UniProt Acc URLs Voltage dependent P/Q type calcium channel-Homo sapiens "RecName: Full=Voltage-dependent P/Q-type calcium channel subunit alpha-1A;AltName: Full=Voltage-gated calcium channel subunit alpha Cav2.1;AltName: Full=Calcium channel, L type, alpha-1 polypeptide isoform 4;AltName: Full=Brain calcium channel I; Short=BI;" CACNA1A; CACH4; CACN3; CACNL1A4 O00555 E S V                                           Voltage dependent R type calcium channel Name Description Gene Names UniProt Acc URLs Voltage dependent R type calcium channel-Homo sapiens "RecName: Full=Voltage-dependent R-type calcium channel subunit alpha-1E;AltName: Full=Voltage-gated calcium channel subunit alpha Cav2.3;AltName: Full=Calcium channel, L type, alpha-1 polypeptide, isoform 6;AltName: Full=Brain calcium channel II; Short=BII;" CACNA1E; CACH6; CACNL1A6 Q15878 E S V                   Phosphodiesterases                               Calmodium/calcium-dependent PDEases                                           Phosphodiesterase 1A Name Description Gene Names UniProt Acc URLs Phosphodiesterase 1A-Homo sapiens "RecName: Full=Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; Short=Cam-PDE 1A; EC=3.1.4.17;AltName: Full=61 kDa Cam-PDE; Short=hCam-1;" PDE1A P54750 E S V                                           Phosphodiesterase 1B Name Description Gene Names UniProt Acc URLs Phosphodiesterase 1B-Homo sapiens "RecName: Full=Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; Short=Cam-PDE 1B; EC=3.1.4.17;AltName: Full=63 kDa Cam-PDE;" PDE1B; PDE1B1; PDES1B Q01064 E S V                               cAMP-specific PDEases                                           Phosphodiesterase 4B Name Description Gene Names UniProt Acc URLs Phosphodiesterase 4B-Homo sapiens "RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4B; EC=3.1.4.17;AltName: Full=DPDE4;AltName: Full=PDE32;" PDE4B; DPDE4 Q07343 E S V                               Rhodopsin-sensitive cGMP-specific PDEases                                           Phosphodiesterase 6 Name Description Gene Names UniProt Acc URLs Phosphodiesterase 6-Homo sapiens-1 "RecName: Full=Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; Short=GMP-PDE alpha; EC=3.1.4.35;AltName: Full=PDE V-B1;" PDE6A; PDEA P16499 E S V Phosphodiesterase 6-Homo sapiens-2 "RecName: Full=Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta; Short=GMP-PDE beta; EC=3.1.4.35;Flags: Precursor;" PDE6B; PDEB P35913 E S V Phosphodiesterase 6-Homo sapiens-3 "RecName: Full=Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Short=GMP-PDE delta;AltName: Full=Protein p17;" PDE6D; PDED O43924 E S V Phosphodiesterase 6-Homo sapiens-4 "RecName: Full=Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Short=GMP-PDE gamma; EC=3.1.4.17;" PDE6G; PDEG P18545 E S V Phosphodiesterase 6-Homo sapiens-5 "RecName: Full=Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Short=GMP-PDE gamma; EC=3.1.4.17;" PDE6H Q13956 E S V                   Phospholipases C                               Phospholipases C beta                                           Phospholipase C beta 1 Name Description Gene Names UniProt Acc URLs Phospholipase C beta 1-Homo sapiens "RecName: Full=1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1; EC=3.1.4.11;AltName: Full=Phosphoinositide phospholipase C;AltName: Full=Phospholipase C-beta-1; Short=PLC-beta-1;AltName: Full=PLC-I;AltName: Full=PLC-154;" PLCB1; KIAA0581 Q9NQ66 E S V                                           Phospholipase C beta 2 Name Description Gene Names UniProt Acc URLs Phospholipase C beta 2-Homo sapiens "RecName: Full=1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2; EC=3.1.4.11;AltName: Full=Phosphoinositide phospholipase C;AltName: Full=Phospholipase C-beta-2; Short=PLC-beta-2;" PLCB2 Q00722 E S V                                           Phospholipase C beta 3 Name Description Gene Names UniProt Acc URLs Phospholipase C beta 3-Homo sapiens "RecName: Full=1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3; EC=3.1.4.11;AltName: Full=Phosphoinositide phospholipase C;AltName: Full=Phospholipase C-beta-3; Short=PLC-beta-3;" PLCB3 Q01970 E S V                                           Phospholipase C beta 4 Name Description Gene Names UniProt Acc URLs Phospholipase C beta 4-Homo sapiens "RecName: Full=1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4; EC=3.1.4.11;AltName: Full=Phosphoinositide phospholipase C;AltName: Full=Phospholipase C-beta-4; Short=PLC-beta-4;" PLCB4 Q15147 E S V                   PI3/PI4 kinases                               Class Ia PI3Ks                                           PI3K alpha Name Description Gene Names UniProt Acc URLs PI3K alpha-Homo sapiens "RecName: Full=Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; EC=2.7.1.153;AltName: Full=PI3-kinase p110 subunit alpha;AltName: Full=PtdIns-3-kinase p110; Short=PI3K;" PIK3CA P42336 E S V                                           PI3K beta Name Description Gene Names UniProt Acc URLs PI3K beta-Homo sapiens "RecName: Full=Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; EC=2.7.1.153;AltName: Full=PI3-kinase p110 subunit beta;AltName: Full=PtdIns-3-kinase p110;AltName: Full=PI3Kbeta; Short=PI3K;" PIK3CB; PIK3C1 P42338 E S V                               Class Ib PI3Ks                                           PI3K gamma Name Description Gene Names UniProt Acc URLs PI3K gamma-Homo sapiens "RecName: Full=Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; EC=2.7.1.153;AltName: Full=PI3-kinase p110 subunit gamma;AltName: Full=PtdIns-3-kinase subunit p110;AltName: Full=PI3Kgamma; Short=PI3K;AltName: Full=p120-PI3K;" PIK3CG P48736 E S V                   Regulators of G-protein signaling                               Regulators of G-protein signaling                                           RGS PX1 Name Description Gene Names UniProt Acc URLs RGS PX1-Homo sapiens RecName: Full=Sorting nexin-13;AltName: Full=RGS domain- and PHOX domain-containing protein;AltName: Full=RGS-PX1 SNX13; KIAA0713 Q9Y5W8 E S V                   Ser Thr protein kinases                               G protein coupled receptor kinases                                           GRK2 Name Description Gene Names UniProt Acc URLs GRK2-Homo sapiens RecName: Full=Beta-adrenergic receptor kinase 1; Short=Beta-ARK-1; EC=2.7.11.15;AltName: Full=G-protein coupled receptor kinase 2 ADRBK1; BARK; BARK1; GRK2 P25098 E S V                                           GRK3 Name Description Gene Names UniProt Acc URLs GRK3-Homo sapiens RecName: Full=Beta-adrenergic receptor kinase 2; Short=Beta-ARK-2; EC=2.7.11.15;AltName: Full=G-protein-coupled receptor kinase 3 ADRBK2; BARK2; GRK3 P35626 E S V                                           GRK4 Name Description Gene Names UniProt Acc URLs GRK4-Homo sapiens RecName: Full=G protein-coupled receptor kinase 4; EC=2.7.11.16;AltName: Full=G protein-coupled receptor kinase GRK4;AltName: Full=ITI1 GRK4; GPRK2L; GPRK4 P32298 E S V                                           GRK6 Name Description Gene Names UniProt Acc URLs GRK6-Homo sapiens RecName: Full=G protein-coupled receptor kinase 6; EC=2.7.11.16;AltName: Full=G protein-coupled receptor kinase GRK6 GRK6; GPRK6 P43250 E S V                               Kinase suppressor of Ras(KSR)                                           Kinase suppressor of Ras(KSR) Name Description Gene Names UniProt Acc URLs Kinase suppressor of Ras(KSR)-Homo sapiens RecName: Full=Kinase suppressor of Ras 1 KSR1; KSR Q8IVT5 E S V                               Protein kinases C(PKC)                                           Protein kinase D Name Description Gene Names UniProt Acc URLs Protein kinase D-Homo sapiens RecName: Full=Serine/threonine-protein kinase D1; EC=2.7.11.13;AltName: Full=nPKC-D1;AltName: Full=Protein kinase D;AltName: Full=Protein kinase C mu type;AltName: Full=nPKC-mu PRKD1; PKD; PKD1; PRKCM Q15139 E S V                               RAF protein kinases                                           Raf1 protein kinase Name Description Gene Names UniProt Acc URLs Raf1 protein kinase-Homo sapiens RecName: Full=RAF proto-oncogene serine/threonine-protein kinase; EC=2.7.11.1;AltName: Full=C-RAF; Short=cRaf;AltName: Full=Raf-1 RAF1; RAF P04049 E S V                   SHC transforming proteins                               SHC transforming proteins                                           SHC transforming protein 1 Name Description Gene Names UniProt Acc URLs SHC transforming protein 1-Homo sapiens RecName: Full=SHC-transforming protein 1;AltName: Full=Src homology 2 domain-containing-transforming protein C1; Short=SH2 domain protein C1 SHC1; SHC; SHCA P29353 E S V                                           SHC transforming protein 2 Name Description Gene Names UniProt Acc URLs SHC transforming protein 2-Homo sapiens RecName: Full=SHC-transforming protein 2;AltName: Full=Src homology 2 domain-containing-transforming protein C2; Short=SH2 domain protein C2;AltName: Full=Protein Sck SHC2; SCK; SHCB P98077 E S V                                           SHC transforming protein 3 Name Description Gene Names UniProt Acc URLs SHC transforming protein 3-Homo sapiens RecName: Full=SHC-transforming protein 3;AltName: Full=Src homology 2 domain-containing-transforming protein C3; Short=SH2 domain protein C3;AltName: Full=Neuronal Shc; Short=N-Shc;AltName: Full=Protein Rai SHC3; NSHC; SHCC Q92529 E S V                   Small GTP-binding proteins                               Rho small GTPases                                           Cdc42 Name Description Gene Names UniProt Acc URLs Cdc42-Homo sapiens RecName: Full=Cell division control protein 42 homolog;AltName: Full=G25K GTP-binding protein;Flags: Precursor CDC42 P60953 E S V                                           Rac Name Description Gene Names UniProt Acc URLs Rac-Homo sapiens-1 RecName: Full=Ras-related C3 botulinum toxin substrate 1;AltName: Full=p21-Rac1;AltName: Full=Ras-like protein TC25;AltName: Full=Cell migration-inducing gene 5 protein;Flags: Precursor RAC1; MIG5 P63000 E S V Rac-Homo sapiens-2 RecName: Full=Ras-related C3 botulinum toxin substrate 2;AltName: Full=p21-Rac2;AltName: Full=Small G protein;AltName: Full=GX;Flags: Precursor RAC2 P15153 E S V Rac-Homo sapiens-3 RecName: Full=Ras-related C3 botulinum toxin substrate 3;AltName: Full=p21-Rac3;Flags: Precursor RAC3 P60763 E S V                                           Rho Name Description Gene Names UniProt Acc URLs Rho-Homo sapiens-1 RecName: Full=Rho-related GTP-binding protein Rho6;AltName: Full=Rho family GTPase 1;AltName: Full=Rnd1;Flags: Precursor RND1; RHO6 Q92730 E S V Rho-Homo sapiens-2 RecName: Full=Rho-related GTP-binding protein RhoN;AltName: Full=Rho family GTPase 2;AltName: Full=Rnd2;AltName: Full=Rho7;Flags: Precursor RND2; ARHN; RHO7 P52198 E S V Rho-Homo sapiens-3 RecName: Full=Rho-related GTP-binding protein RhoE;AltName: Full=Rho family GTPase 3;AltName: Full=Rnd3;AltName: Full=Rho8;AltName: Full=MemB protein;Flags: Precursor RND3; ARHE; RHO8; RHOE P61587 E S V                   TPR repeat proteins                               TPR repeat proteins                                           TPR repeat protein 1 Name Description Gene Names UniProt Acc URLs TPR repeat protein 1-Homo sapiens RecName: Full=Tetratricopeptide repeat protein 1; Short=TPR repeat protein 1 TTC1; TPR1 Q99614 E S V                   Tubulins                               Tubulins                                           Tubulin Name Description Gene Names UniProt Acc URLs Tubulin-Homo sapiens-1 RecName: Full=Tubulin alpha-1A chain;AltName: Full=Tubulin B-alpha-1;AltName: Full=Tubulin alpha-3 chain;AltName: Full=Alpha-tubulin 3 TUBA1A; TUBA3 Q71U36 E S V Tubulin-Homo sapiens-10 RecName: Full=Tubulin beta chain;AltName: Full=Tubulin beta-5 chain TUBB; TUBB5; OK/SW-cl.56 P07437 E S V Tubulin-Homo sapiens-11 RecName: Full=Tubulin beta-1 chain TUBB1 Q9H4B7 E S V Tubulin-Homo sapiens-12 RecName: Full=Tubulin beta-2A chain TUBB2A; TUBB2 Q13885 E S V Tubulin-Homo sapiens-13 RecName: Full=Tubulin beta-2B chain TUBB2B Q9BVA1 E S V Tubulin-Homo sapiens-14 RecName: Full=Tubulin beta-2C chain;AltName: Full=Tubulin beta-2 chain TUBB2C P68371 E S V Tubulin-Homo sapiens-15 RecName: Full=Tubulin beta-3 chain;AltName: Full=Tubulin beta-III;AltName: Full=Tubulin beta-4 TUBB3; TUBB4 Q13509 E S V Tubulin-Homo sapiens-16 RecName: Full=Tubulin beta-4 chain;AltName: Full=Tubulin 5 beta TUBB4; TUBB5 P04350 E S V Tubulin-Homo sapiens-17 RecName: Full=Putative tubulin beta-4q chain TUBB4Q; TUB4Q Q99867 E S V Tubulin-Homo sapiens-18 RecName: Full=Tubulin beta-6 chain TUBB6 Q9BUF5 E S V Tubulin-Homo sapiens-19 RecName: Full=Tubulin beta-8 chain TUBB8 Q3ZCM7 E S V Tubulin-Homo sapiens-2 RecName: Full=Tubulin alpha-1B chain;AltName: Full=Tubulin alpha-ubiquitous chain;AltName: Full=Alpha-tubulin ubiquitous;AltName: Full=Tubulin K-alpha-1 TUBA1B P68363 E S V Tubulin-Homo sapiens-20 RecName: Full=Tubulin epsilon chain;AltName: Full=Epsilon-tubulin TUBE1; TUBE Q9UJT0 E S V Tubulin-Homo sapiens-21 RecName: Full=Tubulin gamma-1 chain;AltName: Full=Gamma-1-tubulin;AltName: Full=Gamma-tubulin complex component 1; Short=GCP-1 TUBG1; TUBG P23258 E S V Tubulin-Homo sapiens-22 RecName: Full=Tubulin gamma-2 chain;AltName: Full=Gamma-2-tubulin TUBG2 Q9NRH3 E S V Tubulin-Homo sapiens-23 RecName: Full=Gamma-tubulin complex component 2; Short=GCP-2; Short=hGCP2;AltName: Full=Spindle pole body protein Spc97 homolog; Short=hSpc97; Short=h103p TUBGCP2; GCP2 Q9BSJ2 E S V Tubulin-Homo sapiens-24 RecName: Full=Gamma-tubulin complex component 3; Short=GCP-3; Short=hGCP3;AltName: Full=Spindle pole body protein Spc98 homolog; Short=hSpc98; Short=h104p TUBGCP3; GCP3 Q96CW5 E S V Tubulin-Homo sapiens-25 RecName: Full=Gamma-tubulin complex component 4; Short=GCP-4; Short=hGCP4;AltName: Full=Hgrip76; Short=h76p TUBGCP4; 76P; GCP4 Q9UGJ1 E S V Tubulin-Homo sapiens-26 RecName: Full=Gamma-tubulin complex component 5; Short=GCP-5 TUBGCP5; GCP5; KIAA1899 Q96RT8 E S V Tubulin-Homo sapiens-27 RecName: Full=Gamma-tubulin complex component 6; Short=GCP-6 TUBGCP6; GCP6; KIAA1669 Q96RT7 E S V Tubulin-Homo sapiens-3 RecName: Full=Tubulin alpha-1C chain;AltName: Full=Tubulin alpha-6 chain;AltName: Full=Alpha-tubulin 6 TUBA1C; TUBA6 Q9BQE3 E S V Tubulin-Homo sapiens-4 RecName: Full=Tubulin alpha-3C/D chain;AltName: Full=Alpha-tubulin 3C/D;AltName: Full=Tubulin alpha-2 chain;AltName: Full=Alpha-tubulin 2 TUBA3C; TUBA2 Q13748 E S V Tubulin-Homo sapiens-5 RecName: Full=Tubulin alpha-3E chain;AltName: Full=Alpha-tubulin 3E TUBA3E Q6PEY2 E S V Tubulin-Homo sapiens-6 RecName: Full=Tubulin alpha-4A chain;AltName: Full=Tubulin alpha-1 chain;AltName: Full=Alpha-tubulin 1;AltName: Full=Testis-specific alpha-tubulin;AltName: Full=Tubulin H2-alpha TUBA4A; TUBA1 P68366 E S V Tubulin-Homo sapiens-7 RecName: Full=Putative tubulin-like protein alpha-4B;AltName: Full=Alpha-tubulin 4B TUBA4B; TUBA4 Q9H853 E S V Tubulin-Homo sapiens-8 RecName: Full=Tubulin alpha-8 chain;AltName: Full=Alpha-tubulin 8;AltName: Full=Tubulin alpha chain-like 2 TUBA8; TUBAL2 Q9NY65 E S V Tubulin-Homo sapiens-9 RecName: Full=Tubulin alpha chain-like 3 TUBAL3 A6NHL2 E S V                   Tyr protein kinases                               Tyr protein kinases                                           Brutons tyrosine kinase Name Description Gene Names UniProt Acc URLs Brutons tyrosine kinase-Homo sapiens RecName: Full=Tyrosine-protein kinase BTK; EC=2.7.10.2;AltName: Full=Bruton tyrosine kinase;AltName: Full=Agammaglobulinaemia tyrosine kinase; Short=ATK;AltName: Full=B-cell progenitor kinase; Short=BPK BTK; AGMX1; ATK; BPK Q06187 E S V                                           Src tyrosine kinase Name Description Gene Names UniProt Acc URLs Src tyrosine kinase-Homo sapiens-1 RecName: Full=Tyrosine-protein kinase CSK; EC=2.7.10.2;AltName: Full=C-SRC kinase;AltName: Full=Protein-tyrosine kinase CYL CSK P41240 E S V Src tyrosine kinase-Homo sapiens-2 RecName: Full=Proto-oncogene tyrosine-protein kinase Src; EC=2.7.10.2;AltName: Full=pp60c-src; Short=p60-Src; Short=c-Src SRC; SRC1 P12931 E S V                                           Tsk tyrosine kinase Name Description Gene Names UniProt Acc URLs Tsk tyrosine kinase-Homo sapiens RecName: Full=Tyrosine-protein kinase ITK/TSK; EC=2.7.10.2;AltName: Full=T-cell-specific kinase;AltName: Full=Tyrosine-protein kinase Lyk;AltName: Full=Kinase EMT ITK; EMT; LYK Q08881 E S V